Back Cover: CuOTf-Catalyzed Selective Generation of 2-Aminopyrimidines from Carbodiimides and Diaryliodonium Salts by a Triple C(sp3 )−H Functionalization (Chem. Eur. J. 4/2017)
نویسندگان
چکیده
منابع مشابه
One‐Pot C−H Functionalization of Arenes by Diaryliodonium Salts
A transition-metal-free, mild, and highly regioselective synthesis of nitroarenes from arenes has been developed. The products are obtained in a sequential one-pot reaction by nitration of iodine(III) reagents with two carbon ligands, which are formed in situ from iodine(I). This novel concept has been extended to formation of aryl azides, and constitutes an important step towards catalytic rea...
متن کاملCopper-catalyzed regioselective reaction of internal alkynes and diaryliodonium salts.
The copper-catalyzed highly regioselective reaction of internal alkynes with diaryliodonium salts was achieved for the first time. α-Arylketones were obtained in moderate to good yields from arylpropargylic alcohols or aryl alkyl alkynes under mild conditions. It was found that the two kinds of substrates underwent two different arylation-oxygenation pathways under different reaction conditions...
متن کاملRegiospecific reductive elimination from diaryliodonium salts.
StereoElectronic Control of Unidirectional Reductive Elimination (SECURE) is provided by the cyclophane substituent on iodine(III). Computational and experimental studies demonstrate that out of plane steric bulk strongly destabilizes the reductive elimination transition state, and leads to regiochemical control. This approach should be general for high valent main group and transition metal ions.
متن کاملC-2 selective arylation of indoles with heterogeneous nanopalladium and diaryliodonium salts.
A simple and efficient method to prepare synthetically useful 2-arylindoles is presented, using a heterogeneous Pd catalyst and diaryliodonium salts in water under mild conditions. A remarkably low leaching of metal catalyst was observed under the applied conditions. The developed protocol is highly C-2 selective and tolerates structural variations both in the indole and in the diaryliodonium s...
متن کاملCuBr catalyzed C-N cross coupling reaction of purines and diaryliodonium salts to 9-arylpurines.
CuBr was found to be an efficient catalyst for the C-N cross coupling reaction of purine and diaryliodonium salts. 9-Arylpurines were synthesized in excellent yields with short reaction times (2.5 h). The method represents an alternative to the synthesis of 9-arylpurines via Cu(II) catalyzed C-N coupling reaction with arylboronic acids as arylating agents.
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ژورنال
عنوان ژورنال: Chemistry - A European Journal
سال: 2016
ISSN: 0947-6539
DOI: 10.1002/chem.201605446